Psoriasis is an inflammatory skin disease, known for its non-contagious nature and typically chronic-relapsing course. This condition is characterized by an accelerated growth of skin cells, leading to the formation of lesions or plaques, marked by redness and desquamation.
The precise causes of psoriasis remain unknown. However, the immune system plays an important role in its onset. The condition can emerge at any age, often triggered by factors such as physical trauma, infections, sunburns, hormonal changes, excessive alcohol consumption, smoking, emotional stress, and certain medications. Genetic predisposition is also common, with several genes potentially contributing to the disease's onset.
Psoriasis manifests as papules and plaques with clear boundaries, covered with silvery-grey scales resulting from accelerated skin cell turnover. These lesions may be asymptomatic or cause occasional mild itching, but their aesthetic implications can be significant.
The severity of the disease and its impact on quality of life vary among individuals. Some may experience a serious form of the disease, psoriatic arthritis, which typically manifests with joint pain, swelling, and stiffness.
Psoriasis presents in several forms, with plaque psoriasis (also known as psoriasis vulgaris) being the most prevalent. This type accounts for approximately 80-90% of all psoriasis cases. The distinct subtypes of psoriasis are primarily categorized by the unique characteristics and appearances of the skin lesions.
The diagnosis of psoriasis typically relies on the clinical appearance and distribution of these lesions. Dermatologists look for well-defined areas of raised red skin that readily develop scales. Despite the clear visual signs, in rare instances where the diagnosis is uncertain, a biopsy might be performed. This histological examination helps to confirm psoriasis and rule out other similar conditions by analyzing a small sample of skin tissue under a microscope.
Psoriasis presents with a range of symptoms, from common to less frequent ones, including:
While there is no definitive cure for psoriasis, numerous therapeutic options aim to manage the disease. For milder forms, treatments may include emollients (creams or ointments), topical medications (including vitamin D analogues, retinoids, tar derivatives, and corticosteroids), and phototherapy. In more severe cases, systemic drugs such as methotrexate, cyclosporine, or biologics may be necessary.
In conclusion, psoriasis is a complex skin disease with a variety of symptoms and forms. Although its exact cause remains unknown, understanding its triggers, symptoms, and available treatments can help manage the condition effectively.