Intestinal Endometriosis: What is it, Causes, Symptoms and Treatment

Intestinal endometriosis, a specific form of endometriosis, is a condition characterized by the abnormal presence of endometrial tissue within the intestine. This condition can lead to a range of symptoms, including abdominal pain, cramps, and irregular bowel movements. The causes of intestinal endometriosis are not fully understood, and diagnosis can be complex, often requiring several investigations. This article explains intestinal endometriosis, its causes, symptoms, diagnosis, and treatment options.

Endometriosis and Ectopic Endometrium

Endometriosis is a gynecological condition found exclusively in females, characterized by the growth of endometrial-like tissue in locations outside the uterus or in abnormal parts of the uterus. This tissue, which typically lines the inside of the uterus, is known as ectopic endometrium when it grows ectopically. The presence of this tissue is a common cause of chronic pelvic pain and a significant factor in potential fertility issues.

In a normal menstrual cycle, the endometrium thickens in preparation for a possible pregnancy and sheds during menstruation if pregnancy does not occur. However, in endometriosis, the ectopic endometrial tissue undergoes similar cyclical changes but is located outside the uterine cavity. This misplaced tissue continues to behave like the uterine endometrium, responding to hormonal signals from the body. As a result, it thickens, breaks down, and bleeds each month. However, unlike the endometrial tissue within the uterus, the blood from this ectopic tissue has no easy exit route. This leads to inflammation, the formation of painful and bloody lesions, and over time can result in the development of scar tissue and adhesions, which can further exacerbate pain and affect the function of reproductive and surrounding organs.

The impact of endometriosis extends beyond physical symptoms; it can also have psychological and social repercussions, affecting quality of life and mental health.

Types of Intestinal Endometriosis

The classification of intestinal endometriosis depends on the depth and extent of the endometrial implantation. It can be categorized into two main types:

  • Superficial Intestinal Endometriosis: This form involves the growth of endometrial tissue on the surface of the intestine. Although it affects the outermost layers, it can still cause significant discomfort and symptoms such as bloating and irregular bowel movements.
  • Deeply Infiltrating Intestinal Endometriosis (DIE): In this more severe form, the endometrial tissue penetrates deeply into the intestinal wall, potentially leading to more serious complications. DIE can cause narrowing of the intestines, leading to pain, cramping, and changes in bowel habits, and may require surgical intervention for relief.

Causes and Risk Factors

The exact causes of intestinal endometriosis remain unclear. However, several theories have been proposed, including retrograde menstruation, dissemination via lymphatic and blood routes, hormonal activity, metaplastic changes, and genetic predisposition.

Certain factors may increase the risk of developing intestinal endometriosis, such as nulliparity (never having given birth), early menarche, late menopause, short menstrual cycles, prolonged menstruation, high estrogen levels, alcohol consumption, family history of endometriosis, and the presence of medical conditions that prevent the normal passage of menstrual flow.

Symptoms and Complications

Intestinal endometriosis can be asymptomatic or symptomatic. When symptomatic, it can present with abdominal pain during defecation, recurrent pelvic-abdominal pain, abdominal cramps, diarrhea alternating with constipation, a sense of abdominal swelling, nausea, fatigue, rectal bleeding during menstruation, pain during sexual intercourse, and heavy menstruation.

Intestinal endometriosis can lead to complications like the formation of endometriotic cysts or adhesions and can impact fertility.

Diagnosis

Diagnosing intestinal endometriosis can be challenging due to its similar symptom profile with other conditions like irritable bowel syndrome. The diagnosis process involves a thorough investigation, including symptom collection, clinical history evaluation, physical examination, gynecological examination, diagnostic imaging, and sometimes, sigmoidoscopy or laparoscopy.

Treatment Options

The treatment of intestinal endometriosis depends on factors like symptom severity and the patient's future pregnancy plans. The two main therapeutic approaches are conservative (drug-based) and surgical. Conservative treatment focuses on controlling pain and other symptoms, while surgical treatment aims to remove the ectopic endometrium.

Prognosis

The prognosis for intestinal endometriosis depends on several factors, some known and others unknown. There is no universally effective treatment, and recurrence is possible after surgery. However, with the right approach to diagnosis and treatment, many individuals with this condition can manage their symptoms and maintain a good quality of life.

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The Wellyme Team

We understand the importance of reliable information, and our goal is to provide you with knowledge that empowers and informs your wellness journey.

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